Easy to read FDA package insert, drug facts, dosage and administration, and adverse effects for Kapvay (clonidine). Concordia Pharmaceuticals Inc.: KAPVAY (clonidine hydrochloride) extended- release is indicated for the treatment of attention deficit. The following text is taken verbatim from the Kapvay package insert: “The dose of Kapvay [ER clonidine], administered either as monotherapy or as adjunctive.
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Make sure to follow all of your doctor’s and therapist’s instructions.
Generic alternatives may be available. Before using KAPVAY with other centrally active depressants such as phenothiazines, barbiturates, or benzodiazepinesconsider the potential for additive sedative effects. All these effects in male were not reversed at the paackage of a 4-week recovery period. KAPVAY taken with alcohol or medicines that cause sleepiness or dizziness may make your sleepiness or dizziness worse.
The impact of renal impairment on the pharmacokinetics of clonidine in children has not been assessed. When initiating treatment, provide dosage escalation instructions [see Dosage and Administration 2.
The inactive ingredients are sodium lauryl insrt, lactose monohydrate, hypromellose typepartially pregelatinized starch, colloidal silicon dioxide, and magnesium stearate.
Allergic Reactions Advise patients to discontinue KAPVAY and seek immediate medical attention if any signs or symptoms of a hypersensitivity reaction occur, such as generalized rash, urticaria, or angioedema [see Warnings and Precautions 5. Immediate-release clonidine hydrochloride and KAPVAY have different pharmacokinetic characteristics; dose substitution on a milligram for milligram basis will result in differences in exposure. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital.
Clonidine may help to control your condition but will not cure it. If your pulse is slower or faster than it should be, call your doctor before taking this medication that day. Take the missed dose as soon as you remember it. Take clonidine at around the same times every day.
Do not crush, chew, or break tablets because this will increase the rate of clonidine release. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment: While every effort has been made to assure accurate reproduction, please remember that any visual identification should be considered preliminary.
Monitor blood pressure and heart rate, and adjust dosages accordingly in patients treated concomitantly with antihypertensives or other drugs that can reduce blood pressure or heart rate or increase the risk of syncope. Measure heart rate and blood pressure prior to initiation of therapy, following dose increases, and periodically while on therapy. For more information, ask your doctor or pharmacist.
Since only a minimal amount of clonidine is removed during routine hemodialysis, there is no need to give supplemental KAPVAY following dialysis.
The following serious adverse reactions are described in greater detail elsewhere in labeling:.
Kapvay | FULL Prescribing Information |
Somnolence and sedation were commonly reported adverse reactions in clinical studies. The most common adverse reactions that led to discontinuation imsert somnolence and fatigue. Clonidine tablets Catapres are used alone or in combination with other medications to treat high blood pressure.
In addition to taking medication, making lifestyle changes will also help to control your blood pressure.
Do not let anyone else take your medication. Table 9 Treatment Failure: Clonidine hydrochloride is present in human milk. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. A total of 73 patients experienced treatment failure in the double-blind phase: Patients were maintained at their dose for a minimum of 2 weeks before being gradually tapered down to 0. It may harm them. Browse Drugs and Medicines.
There was no effect on reproduction or sperm analysis in these males. Increase daily dosage in increments of 0. In patients that completed 5 weeks of treatment in a controlled, fixed-dose monotherapy study in pediatric patients, during the treatment period the maximum placebo-subtracted mean change in systolic blood pressure was Advise patients that KAPVAY must be swallowed whole, never crushed, cut, or chewed, and may be taken with or without food.
Alcohol can make the side effects from clonidine worse. Double-Blind Full Analysis Set.
The pharmacokinetic profile of KAPVAY administration was evaluated in an open-label, three-period, randomized, crossover study of 15 healthy adult subjects who received three single-dose regimens of clonidine: Avoid becoming dehydrated or overheated. Clonidine is not a central nervous system stimulant.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.