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Yaws is a non-venereal tropical infectious disease caused by the organism Treponema pertenue.[1] This organism is closely related to the. Yaws is an infectious tropical disease caused by the spirochete (spiral shaped) bacterium known as Treponema pertenue. The disease presents in three stages . Yaws is a tropical disease characterized by a primary cutaneous lesion, followed by a granulomatous skin eruption, and sometimes by late destructive lesions of.

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At this stage, swollen glands swollen lymph nodes are not uncommon and the rash may develop a brown crust. Between and overcases were reported to the WHO.

What is Yaws Disease?

Stage 1 and 2 yaws tropial treated with antibiotics, especially tropicall benzathine penicillin G. Retrieved 27 February Radiologic abnormalities reveal dactylitis and osteoperiostitis. Beers MH, Berkow R. The last clinical case in India was reported in and the last latent case in The global prevalence of this disease and the other endemic treponematoses, bejel and pintawas reduced by the Global Control of Treponematoses TCP programme between and from about 50 to million cases to about 2. Until recently, the only treatment for yaws was penicillin administered through injections.

Yaws – NORD (National Organization for Rare Disorders)

These antibiotic drugs may also be used to prevent this disease in family members and others who are in frequent contact with affected individuals. Yaws shows the existence of a circle between disease and poverty, according to which both components feed each other. Examination of remains of Homo erectus from Kenyathat are about 1. It is characterized by lesions of the skin and bones and is caused by a bacteria known as Treponema pallidum II.


Yaws is often distinguished by its late feature of destructive bony disease. History and Physical The disease is characterized by primary, secondary, and tertiary stages. The third, however, may involve complex changes to the bones in many parts of the body. Despite the success of eradication campaigns, there will for years be the challenge of the differential diagnosis, both of the active diseases and their end results.

Investigational Therapies Research on tropical diseases such as yaws is ongoing. There are many clinical similarities but also some obvious differences, which may be due in part to differing sociological and economic backgrounds as well as varying climates and other factors.

Nelson Textbook of Pediatrics. Radius, ulna, and phalanges are the most frequent. Yaws is most commonly seen among children in tropical regions and is spread by skin-to-skin contact. Additionally, as the treponemes are indistinguishable serologically and early clinical features may overlap accurate diagnosis may be difficult.

Enhancing Healthcare Team Outcomes Yaws has required global coordination, as endemic areas often are under-equipped for diagnosis or treatment. Still endemic in some parts of the world.

These secondary lesions frequently ulcerate and are then highly infectious, but heal after six months or more. Yaws has required global coordination, as endemic areas often are under-equipped for diagnosis or treatment.

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From Wikipedia, the free encyclopedia. Turn recording back on. The administration of penicillin requires several components syringes, needles, plastic gloves, water… that make sending the material to remote areas very frajbesia. Andrews’ Diseases of the Skin: Ovine rinderpest Bovine spongiform encephalopathy.

Rare Disease Database

One, known as goundou syndrome, is characterized by inflammation and swelling of the tissues surrounding the nose paranasal swellingas well as overgrowth of the bones in the same region of the face hypertrophic osteitis. Unlike syphilis, yaws is neither sexually transmitted nor transmitted from mother to baby.

The research led by Dr. Stage 3 yaws may be diagnosed by specialized blood tests i. These organisms reproduce every 30 hours and with corkscrew motility these move through connective tissue. Definition The treponematoses are an infection with any treponeme. Another, known as gangosa syndrome also known frambesja rhinopharyngitis mutilansis characterized by degenerative changes of the nose, throat pharynxand the roof of the mouth hard palate. Poverty, crowding, rural settings, and a climate of heavy rainfall and fgambesia humidity are also linked to increased prevalence.